Antibacterial and Antioxidant Activities of Syzygium Aromaticum Capparis Spinosa, and Some Novel Acylselenourea and Acylthourea Derivatives

This study aims to tested the antibacterial and antioxidant activities of two different plant extracts which were Syzygium aromaticum Capparis spinosa, five novel derivatives, i.e. [4-Nitro-N-((4-(N-(pyrimidin-2-yl) sulfamoyl) phenyl) carbamoselenoyl) Benz amide (1), 4-Methyl-N-((4-(N-(pyrimidin-2-yl) (2), sulfamoyl carbamothioyl) (3), 4-Nitro-N-((4-nitrophenyl) carbamo selenoyl) (4), N-(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-1-carbonoselenoyl)-nitrobenzamide (5)] in six concentrations:1,5, 10,25, 50, 100 ug/ml three concentrations. 500,750 ,1000ug/ml synthesis compounds on gram-positive bacteria (Staphylococcus aureus) gram-negative (Escherichia coli). The activity was evaluated with antibiotics susceptible resistant microorganisms. 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging technique used assess activity. findings showed that extract compound 3 more effective against Escherichia coli less Staphylococcus aureus bacteria, whereas spinosa (1, 4, 5) bacteria. oxidation 3) is at concentrations 500, 750, 1000 ineffective 100, 250, while 4 50 only. Compound 5 all